Related Experiment Video
Updated: Jun 26, 2026
Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Prospective randomized controlled trial comparing the use of 3.5-mm and 4.8-mm staples in gastric surgery
Chikara Kunisaki1, Hirochika Makino, Ryo Takagawa
1Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57, Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan. s0714@med.yokohama-cu.ac.jp
Background/Aims:
The purpose of this study was to evaluate and compare the use of 4.8-mm and 3.8-mm staples in gastric resection.
Methodology:
A series of 60 patients underwent distal or proximal gastrectomy. A 4.8-mm GIA universal stapler was randomly assigned for use in 50% of the patients and a 3.5-mm GIA universal stapler was assigned for use in the remaining 50%.
Results:
Bleeding was observed in 20 patients (12 in the 4.8-mm group and eight in the 3.5-mm group). In the 4.8-mm group, bleeding was less frequent in patients with a stomach wall thickness of 7.0-9.0mm. In the 3.5-mm group, bleeding was less frequent in patients with a stomach wall thickness of 5.0-7.0mm. Inappropriate staple formation was observed in patients with thick stomach walls in each group.
Conclusions:
The appropriate staple size for gastric surgery may depend on the thickness of the stomach wall.
