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Updated: Jun 26, 2026

04:36
The Examination of Peroxidase-Positive Leukocytes in Semen
Published on: January 19, 2024
[A preliminary study of pre-analysis quality control for semen analysis]
Yi-Feng Ge1, Chun-Hui Wang, Jin-Chun Lu
1Department of Andrology, PLA Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China.
Zhonghua Nan Ke Xue = National Journal of Andrology
|December 24, 2008
Summary
Semen analysis accuracy is improved by abstaining from tobacco and alcohol. Sperm quality declines significantly with longer post-collection times, highlighting the need for careful pre-analysis procedures.
Area of Science:
- Reproductive Biology
- Andrology
- Laboratory Medicine
Context:
- Semen analysis is crucial for male fertility assessment.
- Pre-analysis factors can significantly impact laboratory results.
- Total Quality Management (TQM) principles are essential for reliable diagnostics.
Purpose:
- To investigate the influence of pre-analysis factors on semen analysis outcomes.
- To identify methods for minimizing pre-analysis variability.
- To ensure accuracy in laboratory semen testing.
Summary:
- Sperm concentration, motility, and progressive motility (grade a+b) were significantly higher in men after abstaining from tobacco and alcohol compared to before.
- Sperm motility and progressive motility significantly decreased with increasing time (0.5-3 hours) post-collection, while sperm concentration remained stable.
- These findings underscore the critical impact of lifestyle choices and sample handling time on semen parameters.
Impact:
- Provides evidence-based recommendations for optimizing semen analysis protocols.
- Emphasizes the importance of patient counseling regarding lifestyle factors.
- Contributes to improving the diagnostic accuracy of male infertility assessments through adherence to TQM.
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