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Updated: Jun 26, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
[Pay great attention to research on monitoring burn shock]
1Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, the Third Military Medical University, Chongqing 400038, PR China.
Abstract:
Improvement in early burn treatment has been realized, the mortality of burn shock has been decreased. However, the treatment of burn shock is still inadequate and occult hypoperfusion is usually occurred. This may be difficult to identify the appropriate resuscitation endpoint. The goal in management of burn shock is restoration of adequate tissue perfusion and normalization of cellular metabolism. Traditional endpoints, such as blood pressure, urine output are useful in managing mild and moderate burn shock. Additional endpoints that evaluate the adequacy of global and regional perfusion and oxygenation at the tissue level should be used in treatment of severe burn injury. Now the most useful parameters may be blood pressure, urine output, serum lactate, BE and CVP, SCVO2.
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