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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

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Related Experiment Video

Updated: Jun 26, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

The appendix on CT.

S Whitley¹, P Sookur, A McLean

¹Sunnybrook Health Sciences Center, Toronto, Ontario, Canada. siobhanwhitley@yahoo.co.uk

Clinical Radiology

|December 24, 2008

Summary

This summary is machine-generated.

Diagnosing appendicitis is challenging. This review details how computed tomography (CT) imaging visualizes the normal appendix and various conditions like appendicitis, Crohn's disease, and tumors.

Related Experiment Videos

Last Updated: Jun 26, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Area of Science:

Radiology
Gastroenterology
Oncology

Background:

Appendicitis diagnosis can be difficult, with a 20% negative appendectomy rate historically accepted.
Severe consequences of appendiceal perforation necessitate accurate diagnosis.
Cross-sectional imaging, particularly CT, is increasingly used for suspected appendicitis in adults.

Purpose of the Study:

To review the computed tomography (CT) appearance of the normal appendix.
To illustrate the CT findings of the appendix in various inflammatory and neoplastic conditions.
To aid clinicians in diagnosing appendicitis and related pathologies using CT.

Main Methods:

Literature review of studies investigating the role of CT in appendicitis diagnosis.
Analysis of CT images demonstrating normal and abnormal appendix appearances.
Synthesis of findings related to appendicitis, Crohn's disease, infections, and tumors.

Main Results:

Detailed description of the normal appendix's appearance on CT.
Illustrations of CT features associated with appendicitis.
Presentation of CT findings for other conditions affecting the appendix, including Crohn's disease, infections, and tumors.

Conclusions:

CT imaging is a valuable tool for evaluating suspected appendicitis.
Understanding normal and abnormal appendix CT appearances improves diagnostic accuracy.
CT aids in differentiating appendicitis from other gastrointestinal and neoplastic diseases.