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Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

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Related Experiment Video

Updated: Jun 26, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

Bryan cervical disc prostheses: preservation of function over time.

Markus Wenger1, Petrus van Hoonacker, Benoit Zachee

  • 1Hirslanden Group, Klinik Beau-Site, Schänzlihalde 11, CH-3000 Bern 25, Switzerland. aerzte.beau-site@hirslanden.ch

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|December 24, 2008
PubMed
Summary

This study shows that 28 of 29 cervical disc prostheses maintained mobility after surgery. This indicates that the surgical protocol helps preserve cervical disc prosthesis function and range of motion.

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Related Experiment Videos

Last Updated: Jun 26, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
05:30

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

Published on: February 14, 2025

Area of Science:

  • Spine surgery
  • Orthopedic biomechanics

Background:

  • Cervical disc prostheses are used to treat disc herniations.
  • Maintaining prosthesis function is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the short-term function and range of motion of cervical disc prostheses.
  • To present a protocol aimed at preserving device function.

Main Methods:

  • A case series of 25 patients undergoing 29 cervical total disc arthroplasties.
  • Dynamic X-ray studies measured prosthesis range of motion and compared it to adjacent segments.
  • Follow-up averaged 22.3 months.

Main Results:

  • All 29 prostheses were correctly positioned without subsidence and showed secondary stability.
  • 28 of 29 prostheses remained mobile (average 9.5 degrees).
  • Prosthesis motion was comparable to adjacent healthy spinal segments.

Conclusions:

  • The presented protocol successfully maintained mobility in 28 of 29 cervical disc prostheses.
  • Prosthesis motion was physiological and similar to adjacent segments.
  • Further long-term studies with larger cohorts are needed.