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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Trajectory-based weight modeling distinguishes pathologic weight loss and predicts adverse events in nonhuman primate allogeneic kidney transplantation.

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Related Experiment Video

Updated: Jun 26, 2026

Intra-Omental Islet Transplantation Using h-Omental Matrix Islet filliNG (hOMING)
07:36

Intra-Omental Islet Transplantation Using h-Omental Matrix Islet filliNG (hOMING)

Published on: March 14, 2019

2008 Update from the Collaborative Islet Transplant Registry.

Rodolfo Alejandro1, Franca B Barton, Bernhard J Hering

  • 1The Diabetes Research Institute, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA.

Transplantation
|December 24, 2008
PubMed
Summary

Islet transplantation significantly improves metabolic control in type 1 diabetes patients. This registry data shows positive impacts on insulin independence and glucose stabilization, supporting its clinical value.

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Related Experiment Videos

Last Updated: Jun 26, 2026

Intra-Omental Islet Transplantation Using h-Omental Matrix Islet filliNG (hOMING)
07:36

Intra-Omental Islet Transplantation Using h-Omental Matrix Islet filliNG (hOMING)

Published on: March 14, 2019

Inguinal Subcutaneous White Adipose Tissue (ISWAT) Transplantation Model of Murine Islets
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A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation
17:42

A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation

Published on: April 13, 2011

Area of Science:

  • Endocrinology and Metabolism
  • Transplantation Immunology
  • Regenerative Medicine

Background:

  • Summarizes efficacy and safety of islet transplantation.
  • Utilizes data from the NIDDK and JDRF funded Collaborative Islet Transplant Registry (CITR).
  • Represents the most comprehensive human-to-human islet transplant data collection.

Purpose of the Study:

  • To report primary efficacy and safety outcomes of islet transplantation.
  • To analyze data from the Collaborative Islet Transplant Registry (CITR).

Main Methods:

  • Collected and monitored allogeneic islet transplantation data.
  • Data sourced from North America, Europe, and Australia since 1999.
  • Included 325 adult recipients and 712 donors as of April 2008.

Main Results:

  • At 3 years, 23% of islet-alone recipients achieved insulin independence.
  • 70% achieved insulin independence at least once, with sustained function at 1 and 2 years.
  • Factors favoring outcomes included higher infusions, more islet equivalents, lower HbA1c, and larger islet size. Protocols with daclizumab or etanercept showed improved outcomes.

Conclusions:

  • Clinical islet transplantation should be evaluated by glucose stabilization and prevention of severe hypoglycemia.
  • Registry results confirm islet transplantation's positive impact on metabolic control in type 1 diabetes.
  • Current approaches using daclizumab or etanercept are supported by improved outcomes.