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A look ahead: PET/MR versus PET/CT.

Gustav K von Schulthess¹, Heinz-Peter W Schlemmer

¹Nuclear Medicine, Department of Medical Radiology, University Hospital, Raemistr. 100, CH-8091, Zurich, Switzerland. gustav.vonschulthess@usz.ch

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Summary

Combining positron emission tomography (PET) and magnetic resonance (MR) is a research focus, but clinical use of fully integrated PET/MR systems is uncertain. Adjacent systems offer a practical approach to evaluate integrated imaging value.

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Area of Science:

Medical Imaging
Nuclear Medicine
Radiology

Background:

Positron emission tomography (PET) and magnetic resonance (MR) integration is gaining interest.
Existing PET/MR and PET/CT imaging data are reviewed.
Different levels of system integration are discussed, from independent to fully integrated systems.

Purpose of the Study:

To differentiate facts from fiction regarding integrated PET/MR systems.
To analyze the implications of simultaneous data acquisition in combined PET/MR imaging.
To assess the current and future value of integrated PET/MR technology.

Main Methods:

Review of existing literature on combined PET/MR and PET/CT imaging.
Analysis of different system integration approaches (independent, adjacent, fully integrated).
Discussion on the relevance of technical simultaneity versus pharmacokinetic considerations.

Main Results:

PET/MR integration is an interesting research area with an uncertain outcome.
Simultaneous brain PET/MR applications are of immediate research interest.
Clinical applications do not yet justify fully integrated PET/MR systems.

Conclusions:

Adjacent PET/MR systems with patient shuttles are a pragmatic starting point.
The clinical value of fully integrated PET/MR systems remains to be determined.
Further research is needed to establish the role of integrated PET/MR in clinical practice.