Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cytokine receptors.

S Gillis1

  • 1Immunex Research and Development Corporation, Seattle, Washington 98101.

Current Opinion in Immunology
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Molecular characterization of cytokine receptors has advanced rapidly. Understanding these interactions is key for developing new therapeutic drugs targeting cytokine function.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improving outcomes in patients with Acute Kidney Injury: the impact of hospital based automated AKI alerts.

Postgraduate medical journal·2015
Same author

Interleukins: a rose is a rose ….

Immunology today·2014
Same author

T-cell growth factors: interleukin 2.

Immunology today·2014
Same author

Near-hanging as presenting to hospitals in Queensland: recommendations for practice.

Anaesthesia and intensive care·2006
Same author

Abnormal cervical cytology: a risk factor for endometrial cancer recurrence.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2005
Same author

Practical and dosimetric implications of a new type of packaging for radiographic film.

Physics in medicine and biology·2005
Same journal

A blind spot of human T cell immunology: epitope specificity in secondary lymphoid organs.

Current opinion in immunology·2026
Same journal

Germinal center responses at barrier organ sites.

Current opinion in immunology·2026
Same journal

Ocular sarcoidosis: from clinical signs to targeted interventions.

Current opinion in immunology·2026
Same journal

On or within: spatial determinants of antigen handling in the nasal turbinates.

Current opinion in immunology·2026
Same journal

Decoding the complexity of intestinal immunity with spatial transcriptomics.

Current opinion in immunology·2026
Same journal

Reconsidering the immunological aspects of solid-phase assays for antiphospholipid antibodies detection.

Current opinion in immunology·2026
See all related articles

Area of Science:

  • Immunology
  • Molecular Biology
  • Pharmacology

Background:

  • Recent advancements in radiolabeled cytokines and cell line development have accelerated research.
  • Significant progress has been made in understanding cytokine receptor molecular characterization.

Purpose of the Study:

  • To highlight the rapid progress in molecular characterization of cytokine receptors.
  • To underscore the therapeutic potential of targeting ligand-receptor interactions.

Main Methods:

  • Utilizing radiolabeled cytokines for receptor studies.
  • Employing cell lines with high receptor expression for molecular analysis.

Main Results:

  • Establishment of multiple cytokine-receptor gene families.
  • Identification of ligand-receptor interactions as a potential therapeutic target.

    • Conclusions:

    • The molecular understanding of cytokine receptors is rapidly evolving.
    • Inhibiting cytokine function via ligand-receptor blockade presents a promising therapeutic avenue.