Related Experiment Video
Updated: Jun 26, 2026

Rearing the Cabbage White Butterfly (Pieris rapae) in Controlled Conditions: A Case Study with Heavy Metal Tolerance
Published on: August 18, 2023
Cardiovascular effects of lead exposure
1Division of Nephrology & Hypertension, University of California, Irvine, California 92697, USA. ndvaziri@uci.edu
Abstract:
Several epidemiological and clinical studies have found a link between chronic lead exposure and elevated blood pressure. In addition, a few population studies have shown possible connection between lead exposure and other cardiovascular disorders including ischaemic coronary heart disease, cerebrovascular accidents, and peripheral vascular disease. The causal link between chronic lead exposure and hypertension (HTN) has been confirmed by several studies in experimental animals. In addition, the effects of lead on the heart and vascular function have been explored in a limited number of in vivo and in vitro studies. The in vivo, ex vivo and in vitro studies conducted in laboratory animal, cultured cells and isolated tissues have helped to elucidate many of the mechanisms by which lead exposure can cause HTN and cardiovascular disease. This review is intended to provide an overview of the epidemiology and the underlying mechanisms of lead-associated HTN and cardiovascular disease.
Related Concept Videos
The Periodic Table and Organismal Elements
Periodic Table Provides Information...
The Periodic Table and Organismal Elements
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Cardiovascular System Abnormal Findings I: Inspection and Palpation
Abnormal findings observed during an inspection