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Updated: Jun 26, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
[Multimodal therapy for juvenile advanced rectal carcinoma]
Yoshihiro Katsumoto1, Noriko Aritake, Hirofumi Yamamoto
1Dept. of Surgery, Veritas Hospital.
Abstract:
A 37-year-old male with locally advanced rectal carcinoma and liver metastasis was treated by multimodal therapy. Since he had severe anemia and perineal abscess, sigmoid colostomy was constructed. After his general condition was recovered, the patient received systemic chemotherapy with mFOLFOX6 (6 courses) and whole pelvic irradiation (40 Gy). The rectal tumor showed a reduction in size, total pelvic evisceration combined with reconstruction of ileal conduit and rectus abdominus myocutaneous (RAM) flap were performed. He was followed by 7 courses of systemic chemotherapy with mFOLFOX6 and bevacizumab. After partial hepatic resection, he was followed by systemic chemotherapy with FOLFIRI and bevacizumab as an outpatient. Recent studies for outcomes in young colorectal carcinoma patients showed that the poor prognosis was not caused by its proper aggressiveness in biologic behavior but just the late diagnosis.
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