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Updated: Jun 26, 2026
07:51
Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
[Will penetrating keratoplasty become obsolete?]
1Service d'Ophtalmologie, CHU Morvan, Brest. beatrice.cochener-lamard@chu-brest.fr
Journal Francais D'Ophtalmologie
|December 25, 2008
Summary
Lamellar keratoplasty offers a breakthrough in corneal grafting, reducing complications like graft rejection and edema seen in penetrative keratoplasty. This advanced technique promises faster visual recovery and improved outcomes for many patients.
Area of Science:
- Ophthalmology
- Regenerative Medicine
- Biomedical Engineering
Context:
- Penetrative keratoplasty (PKP) faces limitations including intraocular pressure elevation, graft rejection, and irreversible edema.
- Advancements in surgical technology are crucial for improving corneal transplantation outcomes.
Purpose:
- To explore the advantages of lamellar keratoplasty over traditional penetrative keratoplasty.
- To discuss the future role and potential improvements of lamellar keratoplasty in corneal grafting.
Summary:
- Lamellar keratoplasty enables the exchange of only diseased corneal layers, potentially avoiding PKP complications.
- This approach may lead to faster visual rehabilitation and enhanced visual performance compared to PKP.
- Despite lamellar advancements, PKP will persist for specific indications, enhanced by femtosecond laser technology and immunomodulation control.
Impact:
- Lamellar keratoplasty represents a significant advancement in corneal grafting, offering improved patient outcomes.
- The development of precise surgical techniques like lamellar keratoplasty is vital for the future of ophthalmology.
- Further research and technological integration will refine lamellar keratoplasty, maximizing its clinical benefits.
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