Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a vitamin-related gene signature to predict the immune characteristics and prognosis of glioma.

Biochemical and biophysical research communications·2026
Same author

Artificial Intelligence with Robotics for Metabolic Rehabilitation and Enhanced Patient Recovery in Critical Care.

Research (Washington, D.C.)·2026
Same author

Glymphatic system metrics derived from DTI-ALPS are associated with cognitive impairment, brain atrophy, and plasma tauopathy biomarkers of type 2 diabetes patients: Analysis in dual-cohort.

Journal of Alzheimer's disease : JAD·2026
Same author

YOLO-Crack: Geometry-Guided Real-Time Crack Detection Framework Toward Edge Deployment.

Sensors (Basel, Switzerland)·2026
Same author

Advancing precision risk stratification in adult diffuse gliomas through DSC-MRI-based habitat analysis.

BMC medical imaging·2026
Same author

Double mini-locking plates for unstable Danis-Weber B distal fibular fractures: superior functional outcomes and lower implant removal rates.

Journal of orthopaedic surgery and research·2026

Related Experiment Video

Updated: Jun 26, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Diffusion-weighted single-shot echo planar MR imaging of normal human prostate using different b values.

Haojun Shi1, Xiangquan Kong, Gansheng Feng

  • 1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. doc_shj@126.com

Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban
|December 25, 2008
PubMed
Summary

Diffusion-weighted MRI (DWI) using SE-EPI sequences effectively images the prostate. Apparent diffusion coefficient (ADC) values are higher in the peripheral zone than the central gland in healthy prostates.

More Related Videos

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Related Experiment Videos

Last Updated: Jun 26, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Area of Science:

  • Magnetic Resonance Imaging
  • Radiology
  • Biomedical Engineering

Background:

  • Diffusion-weighted MRI (DWI) is crucial for prostate imaging.
  • Understanding normal prostate tissue characteristics is essential for detecting abnormalities.
  • Optimizing DWI parameters, such as b values, is key for image quality and diagnostic accuracy.

Purpose of the Study:

  • To evaluate the impact of varying b values on prostate DWI using SE-EPI sequences.
  • To characterize normal prostate anatomy and measure apparent diffusion coefficient (ADC) values.
  • To assess image quality and contrast between different prostatic regions.

Main Methods:

  • Utilized a 1.5T MRI system with a phased array surface multicoil.
  • Employed single-shot spin echo echo planar imaging (SE-EPI) sequences for DWI.
  • Acquired images from 24 healthy volunteers using b values of 0, 30, 300, 500, and 1000 s/mm(2).

Main Results:

  • Successfully obtained high-quality prostate DWI images without artifacts in all volunteers.
  • Observed good contrast between the peripheral zone (PZ) and central gland (CG), influenced by b values.
  • Measured significantly higher ADC values in the PZ ((1.27±0.22)x10(-3) mm(2)/s) compared to the CG ((1.01±0.17)x10(-3) mm(2)/s).

Conclusions:

  • Single-shot echo planar imaging (SE-EPI) is a suitable DWI sequence for the human prostate.
  • Low b values enhance contrast between PZ and CG, while high b values ensure accurate diffusion and ADC measurements.
  • Normal prostatic tissue exhibits higher ADC values in the PZ than the CG, indicating diffusional anisotropy.