Related Experiment Video
Updated: Jun 26, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
Recent advances in the methodology, optimisation and application of MEEKC
Richie Ryan1, Sheila Donegan, Joe Power
1Waterford Institute of Technology, Cork Road Campus, Waterford, Ireland. rjryan@wit.ie
Abstract:
MEEKC is an electrodriven separation technique. Oil-in-water microemulsions (MEs) and to a lesser extent water-in-oil MEs have been used in MEEKC as BGEs to achieve separation of a diverse range of solutes. The more common (oil-in-water) MEs are composed of nanometre-sized droplets of oil suspended in an aqueous buffer. Interfacial tension between the oil and aqueous phase is reduced close to zero by the presence of a surfactant and a co-surfactant. MEEKC is capable of providing fast and efficient separations for a wide range of acidic, basic and neutral, water-soluble and -insoluble compounds. This review details the advances in MEEKC-based separations from the period 2006 to 2008. Areas covered include online sample concentration, chiral separation, suppressed electroosmosis MEEKC, MEEKC-MS, and the use of MEEKC in predicting migration behaviour and solute characteristics. A fundamental introduction to MEEKC, along with the presentation and discussion of recent applications is also included.
Related Concept Videos
Methods of Medium Optimization
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Kaplan-Meier Approach
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation
On...
Optimization Problems