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A two-year clinical lifestyle intervention program for weight loss in obesity

Karin Andersson1, Brita Karlström, Susanne Fredén

  • 1Department of Public Health and Caring Sciences/Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden.

Food & Nutrition Research
|December 26, 2008
PubMed
Abstract

Insights

This 2-year clinical lifestyle intervention program successfully reduced weight, sagittal abdominal diameter (SAD), and triglycerides in overweight and obese patients. The program demonstrated feasibility in clinical practice with acceptable dropout rates.

Area of Science:

  • Clinical Practice
  • Obesity Management
  • Metabolic Health

Background:

  • Lifestyle interventions in randomized studies yield ~5% weight loss.
  • Obesity is a significant public health concern linked to metabolic risk factors.

Purpose of the Study:

  • To evaluate a 2-year clinical group intervention for lifestyle modification.
  • Assess impact on weight loss and metabolic risk factors: SAD, triglycerides, fasting glucose, and blood pressure.

Main Methods:

  • A 2-year ongoing group intervention program focused on diet and physical activity.
  • 151 women and 36 men with obesity (BMI > 30) participated.
  • Follow-up involved regular clinical visits.

Main Results:

  • Significant weight loss achieved: 3.8 kg in women, 4.4 kg in men.
  • Reduced sagittal abdominal diameter (SAD) by 5% and triglycerides by 16-24%.
  • Slight, non-significant increases in systolic and diastolic blood pressure observed.

Conclusions:

  • A clinical lifestyle intervention program is feasible for outpatients.
  • The program effectively reduces weight, SAD, and triglycerides.
  • Achieved comparable or lower dropout rates than clinical trials.
Keywords:
food intakeoverweightphysical activitysagital abdominal diametertriglyceridesweight changes

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