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Related Concept Videos

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Related Experiment Video

Updated: Jun 26, 2026

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
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Published on: December 7, 2021

SimHap GUI: an intuitive graphical user interface for genetic association analysis.

Kim W Carter1, Pamela A McCaskie, Lyle J Palmer

  • 1Western Australian Institute for Medical Research and UWA Centre for Medical Research, University of Western Australia, Perth, Australia. kcarter@ichr.uwa.edu.au

BMC Bioinformatics
|December 27, 2008
PubMed
Summary

SimHap GUI offers a user-friendly graphical interface for genetic association analysis, simplifying complex tasks for researchers. This tool enhances the SimHap R package, making single nucleotide polymorphism (SNP) and haplotype analysis accessible to a wider audience.

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Last Updated: Jun 26, 2026

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Area of Science:

  • Genetics
  • Bioinformatics
  • Epidemiology

Background:

  • Genetic association analysis, particularly involving single nucleotide polymorphisms (SNPs) and haplotypes, often lacks accessible graphical tools.
  • Existing tools like the SimHap R package require advanced statistical and informatics expertise, limiting their usability for many researchers.

Purpose of the Study:

  • To develop a user-friendly, cross-platform graphical analysis tool for genetic association studies.
  • To provide an accessible interface for both novice and advanced users to perform SNP and haplotype association analyses.

Main Methods:

  • Development of SimHap GUI, a graphical user interface integrated with the SimHap R package.
  • Implementation of a novel workflow interface guiding users through analysis steps.
  • Inclusion of enhanced functionalities: data checking, automated data conversion, and simulation progress monitoring.

Main Results:

  • SimHap GUI provides an integrated graphical environment for epidemiological, single SNP, and haplotype-based association analysis.
  • The tool features a workflow interface that simplifies the analysis process.
  • Enhanced functionalities include robust data checking, automated conversion, and real-time simulation progress tracking.

Conclusions:

  • SimHap GUI offers an easy-to-use, cross-platform solution for various genetic association analyses.
  • It serves as a free alternative to commercial statistical packages, specifically tailored for genetic association studies.