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A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
Published on: October 15, 2013
A hydrogel based fluorescent micro array used for the characterization of liquid analytes.
A R Thete1, T Henkel, R Göckeritz
1Department of Physical Chemistry and Microreaction Technologies, Institute for Micro and Nano Technologies, Technical University of Ilmenau, Ilmenau, Germany. aniket.thete@tu-ilmenau.de
Analytica Chimica Acta
|December 27, 2008
Summary
This study introduces an optochemical tongue, a fluorimetric micro spot array for analyzing liquid samples. This innovative sensor array provides specific analytical information from non-specific recognition, enabling quality control applications like identifying alcoholic beverages.
Area of Science:
- Analytical Chemistry
- Materials Science
- Spectroscopy
Background:
- Development of sensors for liquid sample analysis is crucial for quality control.
- Existing methods often rely on specific recognition, limiting versatility.
- Non-specific recognition offers a promising alternative for complex mixture analysis.
Purpose of the Study:
- To describe a novel fluorimetric micro spot array for liquid sample analysis.
- To demonstrate the array's capability for characterizing solvent mixtures and identifying alcoholic beverages.
- To establish the array as an 'optochemical tongue' analogous to electronic noses and tongues.
Main Methods:
- Fabrication of a micro spot array using binary mixtures of fluorescence dyes in a hydrogel matrix.
- Utilizing changes in fluorescence wavelength and intensity due to dye-surrounding interactions for analysis.
- Analyzing fluorescence patterns and intensity changes for specific analytical information.
Main Results:
- The fluorimetric micro spot array successfully characterized solvent mixtures.
- Specific analytical information was obtained through a non-specific recognition approach.
- The array demonstrated effectiveness in identifying alcoholic beverages for quality control.
Conclusions:
- The developed optochemical tongue offers a new approach for liquid sample analysis.
- Non-specific recognition using fluorescence arrays can yield specific and valuable analytical data.
- This technology has potential applications in quality control and chemical sensing.
