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Updated: Jun 26, 2026
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Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
Published on: September 8, 2021
Visualization of neuromelanin in the Substantia nigra and locus ceruleus at 1.5T using a 3D-gradient echo sequence
Toshiki Nakane1, Takashi Nihashi, Hisashi Kawai
1Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan. raizo@med.nagoya-u.ac.jp
Abstract:
Recent technical advances have enabled the visualization of neuromelanin in the substantia nigra pars compacta (SNc) and locus ceruleus (LC) by 3-tesla (T) magnetic resonance imaging in vivo. In the present study, we successfully detected neuromelanin in the SNc and LC of 6 healthy volunteers at 1.5T using a 3D gradient echo sequence with off-resonance magnetization transfer contrast.
