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Updated: Jun 26, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
Pulmonary edema associated with methylene blue dye administration during sentinel lymph node biopsy
Daniel Teknos1, Alexius Ramcharan, Soji F Oluwole
1Department of Surgery, Harlem Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10037, USA. daniel_teknos@hotmail.com
Abstract:
Sentinel lymph node biopsy (SLNB) is an established procedure for staging early breast cancer. Recently, methylene blue dye has been advocated as a safe, efficacious and cost-effective substitute for isosulfan blue in sentinel lymph node mapping. In this case report, we describe a 44-year-old woman who developed pulmonary edema associated with the use of methylene blue dye for SLNB.
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