Related Experiment Video
Updated: Jun 26, 2026
08:18
Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
[Orbital tumors in adults--a 10-year study]
J Krásný1, J Sach, R Brunnerová
1Ocní klinika FN Královské Vinohrady, Praha.
Summary
Orbital tumors in adults are most commonly inflammatory pseudotumors and lymphomas. Histological verification is crucial for directing effective orbital tumor treatment and management.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Review of 87 adult patients with orbital tumors diagnosed and treated between 1998 and 2007.
- Patient cohort included 42 men and 45 women, aged 18-89 years.
- Tumor origins: 49 benign (median age 48) and 38 malignant (median age 61).
Observation:
- Magnetic resonance imaging (MRI) and histological verification were primary diagnostic methods.
- 64 tumors required 70 surgical procedures, with anterior orbitotomy being most common (72.5%).
- 23 patients received non-surgical treatment (corticosteroids) or were monitored for benign tumors.
Findings:
- Inflammatory pseudotumors were the most frequent diagnosis (40%), treated primarily with corticosteroids.
- Lymphoma (19.5%) showed high remission rates with chemotherapy; MALT-lymphoma comprised 59% of cases.
- Malignant tumors, including primary carcinomas and secondary melanomas, necessitated orbital exenteration in severe cases.
Implications:
- Histological verification is the definitive step in diagnosing orbital tumors and guiding subsequent therapy.
- Management strategies vary significantly based on tumor type, ranging from corticosteroids to chemotherapy and surgery.
- Early and accurate diagnosis is critical for improving outcomes in patients with orbital malignancies.
