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Updated: Jun 26, 2026

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
Published on: February 23, 2020
Search for serum biomarkers associated with abdominal aortic aneurysm growth--a pilot study
M Vega de Céniga1, M Esteban, J M Quintana
1Department of Angiology and Vascular Surgery, Hospital de Galdakao-Usansolo, Bizkaia, Spain. melina.vegadeceniga@osakidetza.net
Introduction:
Serological biomarkers could reflect asymptomatic infrarenal aortic aneurysm (AAA) activity and guide patient management.
Report:
Serum concentrations of C-reactive protein (CRP), alpha 1-antitrypsin and lipoprotein(a) were measured in blood samples from 35 AAA patients and 35 controls and correlated with the aortic diameter and AAA growth in the previous 12 months. We found a positive correlation between CRP and AAA diameter (r=0.46; p=0.007) and alpha 1-antitrypsin and AAA growth (r=0.55; p=0.004).
Conclusions:
Alpha 1-antitrypsin may be a promising biomarker of AAA growth.
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