Related Experiment Video
Updated: Jun 26, 2026

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
Published on: October 24, 2018
Brain-derived neurotrophic factor, stress and depression: a minireview
Burak Yuluğ1, Erol Ozan, Ali Saffet Gönül
1Department of Psychiatry, University of Bern, Bern, Switzerland. yulug@gmx.de
Abstract:
Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family, and is widely expressed in the adult mammalian brain. Besides its well known neuroprotective activity after traumatic brain injury the evidences regarding its activity dependent release by the pathophysiology of major depression are rapidly replicating. Considering the data that stress plays an important role by the development of depression which is characterized with prominent hippocampal cell death, as well as the well known neuroprotective effects of BDNF, we aimed to investigate the link between the BDNF, stress and depression. Thus we prepared a minireview in order to evaluate the neuroprotective role of BDNF by psychiatric disorders which are characterized with prominent neuronal cell death.
More Related Videos
Related Concept Videos
Depression: Overview
Physiological Foundation of Stress
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
Neurogenesis and Regeneration of Nervous Tissue

