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Updated: Jun 26, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Hybrid right-left cardiac resynchronization therapy defibrillator implantation in persistent left superior vena cava
Matteo Anselmino1, Maria Cristina Marocco, Claudia Amellone
1Department of Medicine, Cardiology Unit, University of Turin, Corso Bramante 88, Italy. matt.ans@alice.it
Insights
Persistence of the left superior vena cava (PLSVC) is a rare anomaly affecting transvenous pacing. A hybrid approach for cardiac resynchronization therapy defibrillator implantation in a PLSVC patient proved safe and feasible.
Area of Science:
- Cardiology
- Anatomical Variations
- Electrophysiology
Background:
- Persistence of the left superior vena cava (PLSVC) is a congenital anomaly occurring in approximately 0.3% of the population.
- This variation presents unique challenges for cardiovascular procedures, especially transvenous lead implantation.
- Accurate identification and management strategies are crucial for successful device implantation.
Observation:
- A patient with PLSVC requiring cardiac resynchronization therapy defibrillator (CRT-D) implantation was encountered.
- Standard transvenous lead placement approaches were deemed unsuitable due to the anomalous venous anatomy.
- A hybrid approach combining right-sided access with left-sided lead placement was considered.
Findings:
- The described hybrid right-left approach for CRT-D implantation in a patient with PLSVC was successfully performed.
- The procedure was found to be both feasible and safe, demonstrating effective lead placement.
- This technique offers a viable alternative to surgical implantation in complex cases.
Implications:
- This hybrid technique provides a valuable alternative for challenging CRT-D implantations in patients with PLSVC.
- It may reduce the need for cardiac surgical intervention, potentially lowering procedural risks and costs.
- Further investigation into this approach could refine treatment strategies for patients with complex venous anomalies.
Abstract:
Persistence of the left superior vena cava (PLSVC), observed in 0.3% of the general population as established by autopsy, is an anatomic variation particularly relevant when occurring in patients in need of a transvenous pacing. In this report, we describe a hybrid right-left cardiac resynchronization therapy defibrillator implantation approach in a patient with PLSVC. In our experience, the described approach proved feasible and safe, and may be considered an option in case of complex vein anatomy before referring for cardiac surgical implantation of a left ventricular lead.
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