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Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Source And Potency Of Stem Cells

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

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Updated: Jun 26, 2026

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation

Published on: December 21, 2016

Stem cells: a primer.

Thomas C Y Lin¹, Oscar K S Lee

¹Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan, Republic of China.

The Chinese Journal of Physiology

|December 31, 2008

Summary

This summary is machine-generated.

Stem cells offer revolutionary regenerative medicine potential, advancing treatments for aging and cancer. This review explores stem cell basics, applications, and ongoing research challenges.

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Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells

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Area of Science:

Biomedical Science
Regenerative Medicine
Cell Biology

Background:

Stem cells possess significant therapeutic and biotechnological potential.
They are crucial for understanding aging and cancer.
Regenerative medicine utilizes stem cells to replace damaged tissues.

Purpose of the Study:

To review the fundamental principles of stem cells.
To discuss current advancements in stem cell research.
To explore potential medical applications and challenges.

Main Methods:

Literature review of stem cell research.
Analysis of current stem cell development.
Discussion of therapeutic applications and challenges.

Main Results:

Stem cells are key to regenerative medicine.
They provide insights into aging and cancer biology.
Various applications are emerging, alongside significant challenges.

Conclusions:

Stem cell research is rapidly advancing medical frontiers.
Further research is needed to overcome existing challenges.
Stem cells hold immense promise for future therapies.