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Published on: June 14, 2020
[Research on chemical constituents from stem of Gymnema sylvestre]
Han-shen Zhen1, Xue-yan Zhu, Ru-mei Lu
1College of Pharmaceutical, Guangxi Traditional Chinese Medical University, Nanning 530001, China. 8zhen@163.com
Objective:
To study on the chemical constituents from the stem of Gymnema sylvestre.
Methods:
The constituents were extracted by percolation with ethanol. Then the extract was separated by systemic solvent separation methods. The part of n-butanol extract was isolated and purified by macroporous adsorptive resins, silica gel column chromatography, sephadex gel column chromatography and recrystallization. The isolated compounds were identified by spectrum methods.
Results:
Eight compounds were isolated and identified as fallows: Conduritol A(I), 1-Heptadecanol(II), Stigmasterol glucoside(III), 1-Quercitol(IV), 1-Octadecanol(V), Potassium nitrate(VI), Lupeol cinnamate(VII), Stigmasterol(VIII).
Conclusion:
Chemical compounds II, III, V, VII are firstly obtained from this plant.
