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[Association of glycosylated hemoglobin A1c control with the complications in type 2 diabetic patients]

Ya-bin Jiang1, Li-hong Nie, Chun-xia Jing

  • 1Emergency Department, Medical College of Jinan University, Guangzhou 510630, China. tjiangyb@jnu.edu.cn

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University
|December 31, 2008
PubMed

Insights

Type 2 diabetes patients often have poor glycemic control, with over 64% showing elevated GHbA1c levels. This poor control is linked to increased risks of hypertension, cerebrovascular issues, neuropathy, and fatty liver disease.

Area of Science:

  • Endocrinology
  • Diabetology
  • Public Health

Background:

  • Glycosylated hemoglobin A1c (GHbA1c) is a key indicator of long-term glycemic control in diabetes management.
  • Suboptimal GHbA1c control is a significant risk factor for the development and progression of diabetic complications.

Purpose of the Study:

  • To assess the prevalence of adequate GHbA1c control among type 2 diabetic patients.
  • To examine the association between GHbA1c control levels and the incidence of various diabetic complications.

Main Methods:

  • A cohort of 676 type 2 diabetes patients was analyzed.
  • Patients were stratified into two groups based on GHbA1c levels: ≤7% (good control) and >7% (poor control).
  • Statistical analysis was performed to compare complication rates between the two groups.

Main Results:

  • Only 35.1% of patients achieved good GHbA1c control (≤7%).
  • Poor GHbA1c control (>7%) was significantly associated with higher rates of hypertension (69.9% vs. 55.7%) and cerebrovascular complications (21.8% vs. 8.9%).
  • Higher incidences of diabetic peripheral neuropathy (46.0% vs. 35.0%) and fatty liver (36.9% vs. 25.3%) were observed in patients with poor glycemic control.

Conclusions:

  • Type 2 diabetes patients exhibit a low rate of successful GHbA1c control.
  • Inadequate glycemic management is linked to an increased risk of several diabetic complications.
  • Enhanced diabetic health education and regular GHbA1c monitoring are crucial for improving patient outcomes.
Abstract

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