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[Correlation between magnetic resonance imaging findings and proliferating cell nuclear antigen expression in
Zhi-ming Xiang1, Yu-sheng Hu, Shi-yu Zhao
1Department of CT/MR, Panyu People's Hospital, Guangzhou 511400, China. xzmgz@126.com
Objective:
To study the correlation between magnetic resonance imaging (MRI) findings and proliferating cell nuclear antigen (PCNA) expression in peripheral lung cancer.
Methods:
The expression of PCNA was detected by means of SABC immunohistochemistry in 45 cases of surgically and pathologically confirmed peripheral lung cancer. The correlation between PCNA expression in the tumors and the MRI findings was analyzed.
Results:
PCNA expression was correlated to the differentiation, tumor size, lobulation, and mediastinal lymph node metastasis of the tumors (P<0.05), but not to the histological type, clinical stage, pleural retraction, spiculation, or signal feature.
Conclusion:
Correlations are found between MRI findings of lung cancer and abnormal expression of PCNA.
