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High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
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Published on: July 6, 2012

Size-selective helical stacking and template polymerization of oligosaccharides around a linear polymeric guest

Takanobu Sanji1, Nobu Kato, Masato Tanaka

  • 1Chemical Resources Laboratory, Tokyo Institute of Technology, 4259-R1-13 Nagatsuta, Midori-ku, Yokohama 226-8503, Japan. sanji@res.titech.ac.jp

Angewandte Chemie (International Ed. in English)
|December 31, 2008
PubMed
Abstract

No abstract available in PubMed .

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Oligosaccharide Assembly01:24

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Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
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