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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Related Experiment Video

Updated: Jun 26, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Splenic tuberculosis: a case report.

Abbas Ali Imani Fooladi1, Mohammad Javad Hosseini, Taghi Azizi

  • 1Research Center of Molecular Biology, Department of Pathology, School of Medical Sciences, Baqiyatallah University of Medical Sciences, Tehran, Iran. Imanifouladi.a@gmail.com

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|January 3, 2009
PubMed
Summary
This summary is machine-generated.

Splenic tuberculosis is rare in healthy individuals and challenging to diagnose. This case highlights Mycobacterium tuberculosis infection presenting solely as splenomegaly, confirmed by PCR after splenectomy.

Related Experiment Videos

Last Updated: Jun 26, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Area of Science:

  • Infectious Diseases
  • Pathology
  • Microbiology

Background:

  • Splenic tuberculosis is an uncommon manifestation, particularly in immunocompetent individuals.
  • Diagnostic challenges often hinder the timely identification of Mycobacterium tuberculosis in splenic infections.

Observation:

  • A middle-aged, immunocompetent male presented with left hypochondriac pain and splenomegaly.
  • Imaging confirmed splenomegaly; no respiratory symptoms or fever were present.

Findings:

  • Splenectomy revealed a large, solid mass with caseation and granulomas.
  • Histopathology and PCR confirmed Mycobacterium tuberculosis infection.
  • No evidence of primary infection in the lungs or other organs was found.

Implications:

  • This case underscores the importance of considering splenic tuberculosis in immunocompetent patients with unexplained splenomegaly.
  • Advanced diagnostic techniques like PCR are crucial for confirming Mycobacterium tuberculosis in atypical presentations.
  • Further research into the pathogenesis of isolated splenic tuberculosis is warranted.