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Updated: Aug 12, 2026

08:52
Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
Published on: May 27, 2011
Lymphocyte gene therapy
K W Culver1, W F Anderson, R M Blaese
1National Institutes of Health, Bethesda, MD 20892.
Human Gene Therapy
|January 1, 1991
Abstract:
Genetically corrected T cells are currently under investigation as a treatment for severe combined immunodeficiency disease resulting from a lack of adenosine deaminase (ADA). Monthly injections of these ADA-corrected T cells have resulted in measurable ADA activity in the peripheral blood and the in vivo production of antibody to blood group antigen. Genetically corrected T cells appear to be clinically valuable vehicles for gene therapy.
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