Related Experiment Video
Updated: Jun 26, 2026

Determination of the Procoagulant Activity of Extracellular Vesicle (EV) Using EV-Activated Clotting Time (EV-ACT)
Published on: August 4, 2023
Disseminated intravascular coagulation in a patient undergoing removal of metastatic brain tumor
Ki Seong Eom1, Jong Moon Kim, Tae Young Kim
1Department of Neurosurgery, Wonkwang University College of Medicine, Iksan, Korea.
Abstract:
The authors present a case of 68-year-old woman who underwent resection of a metastatic adenocarcinoma in the left parietooccipital area. The intraoperative course was uneventful; however, after closure of the scalp incision, increased bleeding from the suture line was noted. A computerized tomography scan that was performed immediately after operation revealed acute epidural hemorrhage with mass effect under the bone flap. The patient developed disseminated intravascular coagulation and immediate re-exploration was performed. This patient was successfully treated owing to early recognition of the condition and immediate treatment with transfusion. Neurosurgeons should be alert that hypercoagulabe state is common in cancer patients and consumptive coagulopathy can occur after resection of metastatic brain tumor.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Hemorrhagic Stroke ll: Pathophysiology
