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Pulpal status of human primary teeth with physiological root resorption
Joana Monteiro1, Peter Day, Monty Duggal
1Department of Paediatric Dentistry, Leeds Dental Institute, Leeds, UK.
International Journal of Paediatric Dentistry
|January 6, 2009
Summary
This study investigated changes in human primary teeth pulp during root resorption. While some advanced resorption showed altered innervation, immune cells, and vascularity, overall significant differences were not found, suggesting retained tooth function.
Area of Science:
- Dentistry
- Oral Biology
- Histology
Background:
- Physiological root resorption is a normal process in primary teeth shedding.
- Understanding pulpal changes during this process is crucial for assessing tooth vitality.
Purpose of the Study:
- To determine if pulpal structure changes occur in human primary teeth during physiological root resorption.
- To correlate the degree of root resorption with pulpal innervation, immune cell presence, and vascularity.
Main Methods:
- Examined 64 primary molars using indirect immunofluorescence for neuronal, immune, and vascular markers.
- Quantified marker expression in pulp horns and mid-coronal regions via image analysis.
- Grouped teeth based on the extent of root resorption (less than 1/3, 1/3-2/3, more than 2/3).
Main Results:
- Observed significant variations in pulpal histology among samples.
- Some teeth with advanced resorption showed decreased innervation, increased immune cells, and increased vascularity.
- Pooled data analysis revealed no statistically significant differences in marker expression across resorption groups (P > 0.05).
Conclusions:
- Human primary teeth exhibit some pulpal changes during physiological root resorption.
- These changes were less pronounced than expected, even in advanced resorption.
- Primary teeth may retain sensory, healing, and repair capabilities until late stages of root resorption.
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