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Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

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Updated: Jun 26, 2026

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

Dental pulp stem cells: what, where, how?

Alastair J Sloan1, Rachel J Waddington

  • 1Mineralised Tissue Research Group, Tissue Engineering and Regenerative Dentistry, School of Dentistry Cardiff University, Cardiff, UK. sloanaj@cardiff.ac.uk

International Journal of Paediatric Dentistry
|January 6, 2009
PubMed
Summary

Dental pulp stem cells are crucial for dentine regeneration. Understanding these cells can lead to new tissue engineering and clinical treatments for dental diseases.

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Primary Culture of Dental Pulp Stem Cells
03:45

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
14:52

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

Related Experiment Videos

Last Updated: Jun 26, 2026

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

Primary Culture of Dental Pulp Stem Cells
03:45

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
14:52

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

Area of Science:

  • Dental Biology
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Post-natal dental pulp contains progenitor/stem cells, identified as dental pulp stem cells.
  • These multipotent mesenchymal stem cells possess high self-renewal and proliferative potential.
  • Dental pulp stem cells are vital for dentine regeneration after injury.

Purpose of the Study:

  • To review existing knowledge on dental pulp stem cells.
  • To explore the potential of these cells and related technologies in future clinical applications.
  • To guide strategies for stem cell isolation, recruitment, and utilization in regenerative therapies.

Main Methods:

  • Literature review of stem cell research in dental pulp.
  • Analysis of stem cell characteristics and regenerative potential.
  • Exploration of in situ recruitment and ex vivo tissue engineering approaches.

Main Results:

  • Dental pulp stem cells play a key role in dentine repair and regeneration.
  • Characterization of these cells is essential for developing effective therapeutic strategies.
  • Potential applications include in situ cell recruitment and scaffold-based tissue engineering.

Conclusions:

  • Understanding dental pulp stem cells is critical for advancing regenerative dentistry.
  • Novel clinical treatments may involve harnessing these cells for in situ regeneration or tissue engineering.
  • These approaches promise a new generation of biologically based dental materials and treatments.