Frequency and predictors of urgent coronary angiography in patients with acute pericarditis

Adam C Salisbury1, Cristina Olalla-Gómez, Charanjit S Rihal

  • 1Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Mayo Clinic Proceedings
|January 6, 2009
PubMed

Insights

Urgent coronary angiography is frequently used in acute pericarditis patients, especially with ST-segment elevation. Coronary artery disease was found in one-third of those undergoing the procedure, highlighting the need to differentiate from myocardial infarction.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Diagnostic Imaging

Background:

  • Acute pericarditis is an inflammation of the pericardium.
  • Distinguishing pericarditis from acute coronary syndromes is clinically important.
  • Coronary angiography is a key diagnostic tool for coronary artery disease.

Purpose of the Study:

  • To determine the frequency of urgent coronary angiography in acute pericarditis patients.
  • To identify clinical factors associated with undergoing coronary angiography.
  • To assess the prevalence of coronary artery disease in this cohort.

Main Methods:

  • Retrospective analysis of 238 patients with acute pericarditis (2000-2006).
  • Evaluation of clinical characteristics, electrocardiogram findings, and troponin T values.
  • Analysis of coronary angiography utilization and findings.

Main Results:

  • Coronary angiography was performed in 16.8% of patients.
  • Angiography frequency was 5-fold higher in patients with ST-segment elevation (24.7% vs 4.3%).
  • Typical anginal chest pain, ST-segment elevation, and elevated troponin T were associated with angiography; 35% had coronary artery disease.

Conclusions:

  • Urgent coronary angiography is common in acute pericarditis, particularly with ST-segment elevation and myocardial infarction symptoms.
  • Coronary artery disease is present in about one-third of patients undergoing angiography for suspected cardiac events.
  • Clinicians should consider pericarditis to avoid unnecessary angiography in ST-elevation myocardial infarction patients.
Abstract

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...