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Related Experiment Video

Updated: Jun 26, 2026

Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
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Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration

Published on: May 3, 2017

Deep dopamine extravasation injury: a case report.

Reid A Phillips1, Patricio Andrades, John H Grant

  • 1UAB Cleft and Craniofacial Center, Division of Plastic Surgery, Department of Surgery, University of Alabama at Birmingham, 35233, USA.

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
|January 6, 2009
PubMed
Summary

A dopamine extravasation in an infant with Down's syndrome caused skin necrosis and temporary nerve damage. Conservative wound care and physical therapy led to full recovery within a year.

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Area of Science:

  • Neonatal care
  • Pediatric neurology
  • Dermatology

Background:

  • Dopamine extravasation is a serious complication in neonates.
  • Infants with Down's syndrome may have unique physiological considerations.

Observation:

  • A 3-month-old infant with Down's syndrome experienced massive dopamine extravasation.
  • This resulted in deep skin necrosis and transient brachial plexus palsy.

Findings:

  • Conservative management, including wound care and physical therapy, was effective.
  • Complete wound healing and full brachial plexus recovery were achieved after one year.

Implications:

  • Highlights the importance of vigilant monitoring during dopamine infusion in neonates.

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Last Updated: Jun 26, 2026

Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
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Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration

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Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration
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Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration

Published on: May 9, 2020

  • Suggests conservative management can yield positive outcomes for severe extravasation injuries.
  • Underscores the need for early diagnosis and tailored physical therapy for brachial plexus injuries.