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Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method
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Salivary phosphorus and phosphate content of beverages: implications for the treatment of uremic hyperphosphatemia

Vincenzo Savica1, Lorenzo A Calò, Paolo Monardo

  • 1University of Messina, Messina, Italy. visavica@tin.it

Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
|January 6, 2009
PubMed

Insights

Patients with end-stage renal disease (ESRD) and chronic kidney disease (CKD) show higher salivary phosphate secretion. Serum phosphorus levels correlate with high-phosphate beverage consumption in hemodialysis (HD) patients.

Area of Science:

  • Nephrology
  • Internal Medicine
  • Biochemistry

Background:

  • Hyperphosphatemia is a dangerous complication of end-stage renal disease (ESRD).
  • It is linked to cardiovascular calcification, increasing morbidity and mortality.
  • Current treatments for hyperphosphatemia are insufficient, with only half of ESRD patients meeting K/DOQI guidelines.

Purpose of the Study:

  • To investigate salivary phosphate secretion in hemodialysis (HD) and chronic kidney disease (CKD) patients.
  • To analyze the beverage consumption habits of HD patients regarding phosphate content.
  • To explore the correlation between hyperphosphatemia and beverage phosphate levels in HD patients.

Main Methods:

  • Salivary phosphate secretion was measured in HD and CKD patients.
  • Beverage consumption patterns, specifically phosphate content, were assessed in HD patients.
  • Serum phosphorus levels were correlated with dietary phosphate intake from beverages.

Main Results:

  • Elevated salivary phosphate secretion was observed in both HD and CKD patient groups.
  • A significant relationship was found between serum phosphorus levels and the consumption of high-phosphate beverages among HD patients.

Conclusions:

  • Increased salivary phosphate secretion is characteristic of HD and CKD patients.
  • Dietary choices, particularly high-phosphate beverages, contribute to hyperphosphatemia in HD patients.
Abstract

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