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Related Experiment Video

Updated: Jun 26, 2026

Functional Calcium Imaging in Developing Cortical Networks
16:33

Functional Calcium Imaging in Developing Cortical Networks

Published on: October 22, 2011

Current application and technology of functional multineuron calcium imaging.

Shigehiro Namiki1, Yuji Ikegaya

  • 1Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan.

Biological & Pharmaceutical Bulletin
|January 6, 2009
PubMed
Summary
This summary is machine-generated.

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Functional multineuron calcium imaging (fMCI) advances monitor over a thousand neurons

Area of Science:

  • Neuroscience
  • Optical Imaging
  • Biotechnology

Background:

  • Functional multineuron calcium imaging (fMCI) enables monitoring of neural circuit activity.
  • Somatic Ca(2+) signals are used to infer neuronal firing patterns.
  • fMCI is applied to study neural circuits in both healthy and diseased states.

Purpose of the Study:

  • To review recent technical advancements and applications of fMCI.
  • To highlight innovations in in vitro and in vivo fMCI.
  • To discuss optical technologies for enhanced neural circuit analysis.

Main Methods:

  • In vitro fMCI utilizes multipoint illumination, spinning-disk microscopy, and sensitive cameras.
  • In vivo fMCI research focuses on developing technologies for dynamic recording environments.

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In vivo Neuronal Calcium Imaging in C. elegans
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In vivo Neuronal Calcium Imaging in C. elegans

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Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique
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Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique

Published on: April 8, 2022

Related Experiment Videos

Last Updated: Jun 26, 2026

Functional Calcium Imaging in Developing Cortical Networks
16:33

Functional Calcium Imaging in Developing Cortical Networks

Published on: October 22, 2011

In vivo Neuronal Calcium Imaging in C. elegans
11:06

In vivo Neuronal Calcium Imaging in C. elegans

Published on: April 10, 2013

Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique
11:41

Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique

Published on: April 8, 2022

  • Optical techniques for fast scanning, deep tissue, and mobile animal imaging are explored.

    • Main Results:

    • Sophisticated in vitro fMCI techniques enhance data acquisition quality and resolution.
    • In vivo fMCI is an evolving field with ongoing technological development.
    • Advanced optical imaging methods are crucial for overcoming challenges in real-time neural recording.

    Conclusions:

    • fMCI is a powerful tool for dissecting complex neural circuits.
    • Continued development of optical technologies will expand fMCI capabilities.
    • fMCI promises deeper insights into brain function and dysfunction.