Related Experiment Video
Updated: Jun 26, 2026

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Thrombus aspiration complicated by systemic embolization in patients with acute myocardial infarction
Ming-Shyan Lin1, Lung-Sheng Wu, Nai-Jen Cheng
1Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 199 Tunhwa N. Road, Taipei, Taiwan.
Insights
Thrombus aspiration during percutaneous coronary intervention can cause systemic embolism, affecting the brain or limbs. Using a large-lumen guiding catheter and gentle contrast injection may reduce this risk.
Area of Science:
- Interventional Cardiology
- Vascular Surgery
Background:
- Percutaneous coronary intervention (PCI) is a primary treatment for acute coronary syndrome.
- The "no-reflow" phenomenon, often due to distal embolism, limits PCI's myocardial reperfusion effectiveness.
- Thrombus aspiration is employed to mitigate distal embolism during PCI.
Observation:
- This report details two cases of systemic embolism occurring during thrombus aspiration.
- One patient experienced cerebral artery embolism.
- The other patient suffered a left radial artery embolism.
Findings:
- Systemic embolism is a potential complication of thrombus aspiration in PCI.
- Cerebral and peripheral artery embolism were observed in the presented cases.
- These events highlight risks associated with thrombus aspiration procedures.
Implications:
- Careful technique during thrombus aspiration is crucial to prevent complications.
- Recommendations include using a large-lumen guiding catheter with deep positioning.
- Gentle contrast medium injection is advised to minimize embolism risk during PCI.
Abstract:
Percutaneous coronary intervention (PCI) is the preferred treatment modality for patients with acute coronary syndrome, but the "no-reflow" phenomenon, primarily caused by distal embolism, has hampered the effectiveness of PCI as regards reperfusion of the myocardium. Thrombus aspiration is sometimes used to reduce the incidence of distal embolism, but potentially the procedure may be complicated by upstream thrombus migration and systemic embolism. Two cases of systemic embolism during thrombus aspiration are presented. One patient had embolism of the cerebral artery and the other embolism of the left radial artery. It is suggested that a large-lumen guiding catheter with a deep-seated position and gentle injection of contrast medium should be used for thrombus aspiration.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis I: Introduction
Pulmonary Embolism III: Nursing Management
Pulmonary Embolism I: Introduction
Pulmonary Embolism I: Introduction
