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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Related Experiment Video

Updated: Jun 26, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

Obesity and asthma.

J Delgado1, P Barranco, S Quirce

  • 1Allergy Service, University Hospital Virgen Macarena, Sevilla, Spain. juliodelgadoromero@gmail.com

Journal of Investigational Allergology & Clinical Immunology
|January 7, 2009
PubMed
Summary
This summary is machine-generated.

Obesity is a risk factor for asthma, increasing its prevalence and incidence. Weight management is crucial for treating obese individuals with asthma.

Related Experiment Videos

Last Updated: Jun 26, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

Area of Science:

  • Pulmonary Medicine
  • Immunology
  • Genetics

Background:

  • Asthma and obesity are significant public health concerns with increasing prevalence.
  • Numerous studies indicate a link between obesity and asthma, with obesity often acting as a risk factor.

Purpose of the Study:

  • To explore the multifaceted relationship between asthma and obesity.
  • To review the mechanisms underlying the association between these two conditions.
  • To emphasize the importance of weight management in asthma treatment.

Main Methods:

  • Review of prospective studies correlating body mass index (BMI) with asthma development.
  • Analysis of physiological impacts of obesity on respiratory function.
  • Examination of the role of systemic inflammation and adipokines in asthma pathogenesis.
  • Identification of genetic links between asthma and obesity.

Main Results:

  • Obesity is associated with reduced pulmonary compliance, lung volumes, and airway diameter.
  • Obesity promotes a systemic proinflammatory state, increasing levels of cytokines, chemokines, and adipokines (e.g., IL-6, TNF-alpha, leptin).
  • Studies suggest obesity modestly increases asthma prevalence and incidence, while weight loss may improve asthma outcomes.

Conclusions:

  • Obesity is a significant risk factor for asthma, impacting respiratory mechanics and promoting inflammation.
  • Adipokines released from adipose tissue play a role in the obesity-asthma link.
  • Weight control programs are essential components in managing asthma in obese patients.