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Updated: Jun 26, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
Acute central retinal artery occlusion presenting as CREST syndrome: a case report
Muhammad Sa Raja1, Tarnya Marshall, Ben Jl Burton
1James Paget University Hospital NHS Foundation Trust, Lowestoft Road, Gorleston, Great Yarmouth NR31 6LA, Norfolk, UK. docraja@hotmail.com.
Background:
A 75 year old lady presented with acute central retinal artery occlusion and contralateral cotton wool spots.
Case Presentation:
General physical examination and investigations led to a diagnosis of CREST syndrome; however, association of central retinal artery occlusion with CREST syndrome is not well known. While diabetes, systemic hypertension, carotid atherosclerosis and cardiac pathology are common causes of CRAO it is always important to rule out giant cell arteritis.
Conclusion:
This case highlights that inflammatory causes of central retinal artery occlusion other than giant cell arteritis should also be considered as a possibility to spare unnecessary use of excessive systemic corticosteroids.
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