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Updated: Jun 26, 2026

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry
Published on: September 15, 2020
Simultaneous interferometric measurement of corrosive or demineralizing bacteria and their mineral interfaces
M S Waters1, M Y El-Naggar, L Hsu
1University of Southern California, Department of Molecular and Computational Biology, 1050 Childs Way MCB 201B, Los Angeles, California 90089-2910, USA.
Abstract:
Here, we report simultaneous surface profile measurements of several bacterial species involved in microbially influenced corrosion and their solid-surface interfaces by using vertical scanning interferometry. The capacity to nondestructively quantify microscale topographic changes beneath a single bacterium without its removal offers a unique opportunity to examine in vivo microbe-surface interactions.

