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Pre-admission therapy for childhood acute diarrhoea--a hospital-based study
1Department of Pharmacy, Faculty of Medicine, University of Malaysia, Kuala Lumpur, Malaysia.
Insights
Most children with acute gastroenteritis (AGE) receive suboptimal pre-hospital treatment, with underuse of oral rehydration salts. Education on appropriate AGE management is crucial for better outcomes.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Acute gastroenteritis (AGE) is a leading cause of childhood mortality and morbidity.
- Effective pre-hospital management is critical for reducing severity and improving outcomes.
- Suboptimal treatment prior to hospital admission is a significant concern in pediatric AGE cases.
Purpose of the Study:
- To evaluate the pre-admission management strategies for pediatric patients diagnosed with acute gastroenteritis.
- To identify common medications administered and assess their appropriateness.
- To determine the extent of underutilization of evidence-based treatments like oral rehydration salts.
Main Methods:
- Retrospective observational study analyzing 222 pediatric AGE patient case notes over 12 months.
- Review of pre-admission medications, including classes and specific agents used.
- Comparison of hospital stay duration between patients who received pre-admission treatment and those who did not.
Main Results:
- 154 patients received pre-admission medications, with antipyretics being most common (69.2%), followed by antibiotics (38.5%).
- Oral rehydration salts (ORS) were underutilized (29.4%), despite proven efficacy.
- 70% of admitted children received suboptimal pre-hospital treatment; no significant difference in hospital stay duration was observed based on prior medication use.
Conclusions:
- Pre-hospital management of pediatric AGE is frequently suboptimal, characterized by underutilization of ORS.
- There is a need for increased public education on appropriate and evidence-based treatments for AGE in children.
- Further interventions are required to improve the quality of care for young patients with gastroenteritis before hospital admission.
Abstract:
Acute gastroenteritis (AGE) is a common illness among infants and children contributing to significant mortality and morbidity. As such, appropriate treatment received prior to hospital admission is of utmost importance. This retrospective observational study aimed to determine preadmission management in paediatric patients prior to hospital admission. Two hundred and twenty-two case notes of paediatric AGE patients were reviewed over a 12-month period. One hundred and fifty-four patients received medications prior to admission with 143 (92.9%) patients received known classes of medications. Antipyretic agents were the most commonly prescribed (69.2%), followed by antibiotics (38.5%), anti-emetics (35.7%), oral rehydration salts (29.4%) and antidiarrhoeals (28.0%). The mean duration of stay in hospital was slightly shorter in patients, who received prior medications than those who did not (2.22 vs. 2.32 days respectively). Seventy per cent of children admitted for AGE were treated suboptimally prior to hospital admission with oral rehydration salts being largely under-utilized, despite their proven efficacy and safety. Sex, race and age had no influence on the type of preadmission treatment. A greater effort should be made to educate the general public in the appropriate treatment of AGE.
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