Pre-admission therapy for childhood acute diarrhoea--a hospital-based study

Y J Ng1, Y L Lo, W S Lee

  • 1Department of Pharmacy, Faculty of Medicine, University of Malaysia, Kuala Lumpur, Malaysia.

Insights

Most children with acute gastroenteritis (AGE) receive suboptimal pre-hospital treatment, with underuse of oral rehydration salts. Education on appropriate AGE management is crucial for better outcomes.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Acute gastroenteritis (AGE) is a leading cause of childhood mortality and morbidity.
  • Effective pre-hospital management is critical for reducing severity and improving outcomes.
  • Suboptimal treatment prior to hospital admission is a significant concern in pediatric AGE cases.

Purpose of the Study:

  • To evaluate the pre-admission management strategies for pediatric patients diagnosed with acute gastroenteritis.
  • To identify common medications administered and assess their appropriateness.
  • To determine the extent of underutilization of evidence-based treatments like oral rehydration salts.

Main Methods:

  • Retrospective observational study analyzing 222 pediatric AGE patient case notes over 12 months.
  • Review of pre-admission medications, including classes and specific agents used.
  • Comparison of hospital stay duration between patients who received pre-admission treatment and those who did not.

Main Results:

  • 154 patients received pre-admission medications, with antipyretics being most common (69.2%), followed by antibiotics (38.5%).
  • Oral rehydration salts (ORS) were underutilized (29.4%), despite proven efficacy.
  • 70% of admitted children received suboptimal pre-hospital treatment; no significant difference in hospital stay duration was observed based on prior medication use.

Conclusions:

  • Pre-hospital management of pediatric AGE is frequently suboptimal, characterized by underutilization of ORS.
  • There is a need for increased public education on appropriate and evidence-based treatments for AGE in children.
  • Further interventions are required to improve the quality of care for young patients with gastroenteritis before hospital admission.

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