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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Inhalation Anthrax01:25

Inhalation Anthrax

Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...

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Related Experiment Video

Updated: Jun 26, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Primary cutaneous actinomycosis.

Deena Patil1, B Siddaramappa, B S Manjunathswamy

  • 1Department of Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Nehru Nagar, India.

International Journal of Dermatology
|January 8, 2009
PubMed
Summary
This summary is machine-generated.

Actinomycosis, a rare infection, can affect the skin. This case highlights successful treatment of primary cutaneous actinomycosis on the back using penicillin and sulfonamides, with no recurrence after one year.

Related Experiment Videos

Last Updated: Jun 26, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Dermatology

Background:

  • Actinomycosis is a rare, chronic bacterial infection caused by Actinomyces species.
  • It typically presents as a suppurative, progressive infection in the neck, thorax, or abdomen.
  • Diagnosis often requires high clinical suspicion due to nonspecific symptoms.

Observation:

  • A case of primary cutaneous actinomycosis on the back is presented.
  • The infection presented with few specific clinical symptoms, necessitating a high index of suspicion for diagnosis.
  • The patient's back was the primary site of infection.

Findings:

  • The patient was treated with benzyl penicillin and sulfonamides.
  • Successful treatment resulted in no recurrence of the infection at the 1-year follow-up.
  • This indicates the efficacy of the chosen antibiotic regimen for this specific presentation.

Implications:

  • This case underscores the importance of considering actinomycosis in the differential diagnosis of chronic skin lesions.
  • Prompt diagnosis and appropriate antibiotic therapy, such as benzyl penicillin and sulfonamides, are crucial for successful management.
  • Further research into cutaneous actinomycosis presentations and optimal treatment strategies may improve patient outcomes.