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Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

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Related Experiment Video

Updated: Jun 26, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Lessons learned from two school tuberculosis investigations.

Shu-Hua Wang1, W Garrett Hunt, Dwight A Powell

  • 1Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA. Shu-Hua.Wang@osumc.edu

Journal of Immigrant and Minority Health
|January 8, 2009
PubMed
Summary

Contact investigations following tuberculosis (TB) cases in two students found latent TB infection (LTBI) in 35% of household contacts and 9.3% of high-risk school contacts. Low-risk contact screening identified minimal LTBI cases.

Related Experiment Videos

Last Updated: Jun 26, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Area of Science:

  • Public Health
  • Infectious Disease Epidemiology
  • Tuberculosis Control

Background:

  • Two foreign-born high-school students developed active pulmonary tuberculosis (TB) within two years of immigrating to the U.S.
  • Contact investigations are crucial for identifying and managing TB transmission, especially in school settings.

Purpose of the Study:

  • To report the findings of contact investigations initiated after active TB cases were diagnosed in two high-school students.
  • To evaluate the yield of screening high-risk versus low-risk contacts for latent TB infection (LTBI) and active TB disease.

Main Methods:

  • Screening of household contacts for active TB and LTBI.
  • Contact tracing and screening of identified high-risk and low-risk school contacts.
  • Diagnostic evaluation for active TB disease and testing for LTBI.

Main Results:

  • No active TB disease was found among 20 household contacts, but 7 (35%) had LTBI.
  • Among 104 high-risk school contacts, no active TB was detected, while 7 (9.3%) were diagnosed with LTBI.
  • Screening 683 low-risk contacts yielded 9 (1.5%) LTBI cases, indicating a lower yield compared to high-risk groups.

Conclusions:

  • Contact investigations are essential for TB control, particularly in educational institutions.
  • Screening should prioritize high-risk contacts to maximize the detection of LTBI and active TB disease.
  • Screening low-risk contacts yields a low proportion of positive cases and may not be an efficient use of resources.