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Metoprolol succinate therapy associated with erythema multiforme
Jaekyoung A Hong1, John D Bisognano
1Department of Internal Medicine, Division of Cardiology,University of Rochester Medical Center, Rochester, NY 14642, USA.
Cardiology Journal
|January 9, 2009
Summary
Metoprolol succinate, a common heart medication, can rarely cause erythema multiforme, a skin condition. This case highlights a potential side effect for physicians to consider in patients experiencing these symptoms.
Area of Science:
- Pharmacology
- Dermatology
- Cardiology
Background:
- Metoprolol succinate is a beta-blocker frequently prescribed for hypertension, heart failure, and angina.
- Adverse drug reactions are a critical aspect of patient safety in cardiovascular pharmacotherapy.
Observation:
- A 36-year-old woman experienced erythema multiforme following a low dose of metoprolol succinate.
- The patient also reported symptoms including pruritic burning pain and chills.
Findings:
- This case represents the first documented instance of metoprolol succinate inducing erythema multiforme.
- Erythema multiforme has been previously associated with carvedilol, another beta-blocker.
Implications:
- Physicians should be aware of this rare but serious potential side effect of metoprolol succinate.
- This finding underscores the importance of vigilant monitoring for dermatological adverse events in patients taking cardiovascular medications.
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