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Binge Eating Disorders

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...

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Related Experiment Video

Updated: Jun 26, 2026

Intermittent Binge-Intake Model in Mice

Intermittent Binge-Intake Model in Mice

Published on: January 10, 2025

Binge-like eating in mice.

Daniele Consoli¹, Angelo Contarino, Antoine Tabarin

¹Department of Experimental and Clinical Pharmacology, Medical School, University of Catania, Catania, Italy. consolidaniele@yahoo.it

The International Journal of Eating Disorders

|January 9, 2009

Summary

This summary is machine-generated.

Researchers developed a new mouse model for binge-eating disorder by combining food restriction, palatable food, and stress. This model reliably induces binge-like eating behavior, offering a valuable tool for studying the condition.

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Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

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Last Updated: Jun 26, 2026

Intermittent Binge-Intake Model in Mice

Intermittent Binge-Intake Model in Mice

Published on: January 10, 2025

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

Published on: December 16, 2022

Area of Science:

Neuroscience
Behavioral Science
Animal Models

Background:

Binge-eating disorder is a significant public health concern.
A reliable animal model for binge-eating disorder is lacking.
Understanding the etiological factors is crucial for developing effective treatments.

Purpose of the Study:

To establish a murine model that reliably mimics binge-eating behavior.
To investigate the effects of food restriction, palatable food, and stress on eating behavior in mice.

Main Methods:

Mice were subjected to cycles of food restriction and refeeding with palatable food.
Stress was induced using a forced swimming test.
Eating behavior and depressive-like behaviors were monitored.

Main Results:

At least three cycles of food restriction/refeeding and stress were required to induce binge-like eating behavior.
Binge-like eating was observed within 4-24 hours after stress application.
The induced binge-eating behavior was transient and not associated with depressive-like behaviors.

Conclusions:

The developed protocol effectively models binge-eating behavior in mice.
This model is not confounded by depressive-like symptoms.
The binge-eating behavior induced by this model is temporary, highlighting the need for further research into long-term effects and interventions.