Related Experiment Video
Updated: Jun 26, 2026

Intermittent Binge-Intake Model in Mice
Published on: January 10, 2025
Restraint, hunger, and disinhibition following treatment for binge-eating disorder
Kristina A Downe1, Juli A Goldfein, Michael J Devlin
1Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA.
Objective:
To examine changes in total, flexible and rigid restraint, hunger, and disinhibition in obese individuals with Binge-Eating Disorder (BED), and assess whether these variables are associated with binge abstinence at post-treatment and during two-year follow-up.
Method:
A total of 116 obese individuals with BED were randomized to a 20-week treatment trial plus two-year follow-up. Using the Eating Inventory (EI), we assessed these factors at pretreatment, post-treatment, and follow-up time-points and examined their relationship to binge abstinence at post-treatment, 12- and 24-month follow-up.
Results:
Low disinhibition and high-total restraint are associated with post-treatment binge abstinence. There are no significant relationships between post-treatment EI variables and binge abstinence at 12- and 24-month follow-up.
Discussion:
Reducing disinhibition as well as increasing EI dietary restraint during BED treatment may be important for short-term success.
More Related Videos
Related Concept Videos
Binge Eating Disorders
Bulimia Nervosa
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Regulation of Food Intake
Self-Regulation
CNS Depressants: Alcohol and Nicotine
