Related Experiment Video
Updated: Jun 26, 2026
Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
Modified lateral neck lymphadenectomy: prospective randomized study comparing harmonic scalpel with clamp-and-tie
Paolo Miccoli1, Gabriele Materazzi, Lorenzo Fregoli
1Dipartimento di Chirurgia, Università di Pisa, Pisa, Italy.
Objective:
To compare the use of harmonic scalpel (HS) with clamp-and-tie technique to evaluate their comparative merits in modified lateral lymphadenectomy (LL).
Study Design:
Prospective and randomized.
Subjects And Methods:
Thirty-seven patients were recruited and divided into Group A (conventional; n = 20) and Group B (HS; n = 17). Thyroid volume, neck circumference, operative time, diameter of the tumor and lymph node, drainage volume, pain, and complications were compared. Operation consisted of thyroidectomy and LL.
Results:
Groups were homogeneous for thyroid volume, diameter of thyroid nodule and lymph node, and neck circumference. Operative time was shorter in Group B than in Group A. The fluid collection in the vacuum between 24 and 48 hours and the increase of neck circumference were lower in Group B. Pain was significantly lower in Group B after 12 hours and decrease was faster in Group B.
Conclusion:
The use of HS during LL is as safe as conventional technique and may allow shorter operative time, lower lymphatic spillage, and faster decrease of pain.
