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Related Concept Videos

Layers of Connective Tissue Proper01:21

Layers of Connective Tissue Proper

Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing tearing...
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Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
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Related Experiment Video

Updated: Jun 26, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

[Distress influence in fibromyalgia].

S Stisi1, C Venditti, I Sarracco

  • 1Reparto di Reumatologia, A.O. "Gaetano Rummo", 82100 Benevento, Italia. stefano.stisi@ao-rummo.it

Reumatismo
|January 10, 2009
PubMed
Summary

Fibromyalgia syndrome (FM) patients perceive significantly higher stress levels than healthy individuals. This suggests FM may stem from a psycho-neuro-endocrinal response to stressors in genetically susceptible individuals.

Area of Science:

  • Psychiatry
  • Neuroscience
  • Pain Management

Context:

  • Fibromyalgia syndrome (FM) is a complex chronic pain condition with unknown etiology.
  • FM is often associated with stressful life events, anxiety, and depression.
  • The relationship between stress and pain perception in FM requires further investigation.

Purpose:

  • To evaluate the role of stressors in fibromyalgia syndrome (FM).
  • To compare stress levels in FM patients, healthy controls, and patients with dysfunctional syndrome.
  • To assess the perceived gravity of stress-generating events in FM.

Summary:

  • Fibromyalgia patients exhibited significantly higher stress scores on both the VRS and IVAS tests compared to healthy controls and dysfunctional syndrome patients.

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Related Experiment Videos

Last Updated: Jun 26, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

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Published on: January 5, 2024

Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
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Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients

Published on: July 14, 2018

  • FM patients also attributed greater significance to individual stressors.
  • These findings highlight the crucial role of perceived stress in FM.

    • Impact:

    • The study supports the hypothesis that FM may result from a psycho-neuro-endocrinal response to stressors in individuals with a genetic predisposition to stress.
    • Emphasizes the importance of addressing perceived stress in managing fibromyalgia.
    • Provides a basis for further research into the neurobiological mechanisms linking stress and FM.