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Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
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[Thrombotic microangiopathies]

J-D Studt1

  • 1Abteilung für Hämatologie, Universitätsspital Basel, Schweiz. studtj@uhbs.ch

Hamostaseologie
|January 10, 2009
PubMed

Thrombotic microangiopathies are disorders of microvascular occlusion and are characterized by thrombocytopenia and microangiopathic haemolytic anaemia. Varying additional signs and symptoms of organ ischaemia may be present. Thrombotic microangiopathies are pathophysiologically heterogenous disorders and include primarily thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome. Besides this, they may occur in association with certain diseases or drugs, or after allogeneic haematopoietic stem cell transplantation.

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