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[A statistical model of evolution with stabilizing selection].

U Bastolla1, L Peliti

  • 1Dipartimento di Fisica, Università La Sapienza, Roma.

Comptes Rendus De L'Academie Des Sciences. Serie III, Sciences De La Vie
|January 1, 1991
PubMed
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This study models asexual reproduction in a fixed population facing random unfit genotypes on a rugged landscape. It computes genetic structure and genetic drift speed in the infinite genome limit.

Area of Science:

  • Evolutionary biology
  • Population genetics

Context:

  • Asexual reproduction dynamics
  • Rugged fitness landscapes
  • Random distribution of unfit genotypes

Purpose:

  • To compute the genetic structure of a population
  • To determine the speed of genetic drift
  • To analyze evolution in a fixed-size population with selection via elimination

Summary:

  • A model of a fixed-size, asexually reproducing population evolving on a rugged fitness landscape is presented.
  • Selection acts through the random elimination of individuals with unfit genomes.
  • The study explicitly computes population genetic structure and genetic drift speed in the infinite genome limit.

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Impact:

  • Provides insights into evolutionary processes in challenging environments.
  • Offers a computational framework for analyzing genetic drift.
  • Contributes to understanding population adaptation and stability.